Etovitae

Symptomatic relief of OA & ankylosing spondylitis (AS); RA; pain & signs of inflammation associated w/ acute gouty arthritis; acute pain including that related to primary dysmenorrhea & minor dental procedure.

OA 30 mg once daily. May be increased to 60 mg once daily in patients w/ insufficient symptomatic relief. Max daily dose: 60 mg. RA 60 mg once daily. May be increased to 90 mg once daily in patients w/ insufficient symptomatic relief. Down-titrate to 60 mg once daily once clinically stabilised. Max daily dose: 90 mg. AS 60 mg once daily. May be increased to 90 mg once daily in patients w/ insufficient symptomatic relief. Down-titrate to 60 mg once daily once clinically stabilised. Max daily dose: 90 mg. Acute gouty arthritis 120 mg once daily for the acute symptomatic period. Max treatment duration: 8 days. Max daily dose: 120 mg. Acute pain 90 mg or 120 mg once daily. Max treatment duration: 8 days. Max daily dose: 120 mg. Primary dysmenorrhea 120 mg once daily. Max daily dose: 120 mg. Post-procedure dental pain 90 mg once daily. Max treatment duration: 3 days. Max daily dose: 90 mg. Hepatic impairment: Moderate (Child-Pugh score 7-9) Max: 60 mg every other day, mild (Child-Pugh score 5-6) Max: 60 mg once daily.

May be taken with or without food.

Hypersensitivity. CHF (NYHA II-IV). Established ischemic heart disease, peripheral arterial disease &/or cerebrovascular disease (including patients who have recently undergone CABG surgery or angioplasty). Patients w/ HTN whose BP has not been adequately controlled. Active peptic ulceration or GI bleeding. Patients who have developed signs of asthma, acute rhinitis, nasal polyps, angioneurotic oedema or urticaria following the administration of ASA or other NSAIDs. Inflammatory bowel disease. Severe hepatic dysfunction (Child-Pugh score >9). Patients w/ estimated CrCl <30 mL/min. Pregnancy & lactation. Childn & adolescents <16 yr.

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

M01AH05 - etoricoxib ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, coxibs.

POM