Pifeltro Dosage & Drug Information

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Core Prescribing Info

Contents

Doravirine

Indications/Uses

HIV-1 w/o past or present evidence of viral resistance to NNRTI in adults in combination w/ other antiretrovirals.

Dosage/Direction for Use

1 tab once daily. Co-administration w/ rifabutin: 1 Pifeltro tab bd (approx 12 hr apart).

Administration

May be taken with or without food.

Contraindications

Co-administration w/ strong CYP450 CYP3A enzyme inducers including anticonvulsants (eg, carbamazepine, oxcarbazepine, phenobarb, phenytoin), androgen receptor inhibitor (eg, enzalutamide), antimycobacterials (eg, rifampin, rifapentine), cytotoxic agent (eg, mitotane), St. John's wort, lumacaftor.

MIMS Class

Antivirals

ATC Classification

J05AG06 - doravirine ; Belongs to the class of non-nucleoside reverse transcriptase inhibitors. Used in the systemic treatment of viral infections.

Regulatory Classification

POM

Presentation/Packing

Form

Pifeltro FC tab 100 mg

Packing/Price

1's

Pifeltro

doravirine

Manufacturer:

Hovione