Romiplate Dosage & Drug Information

Information is sourced from publicly available references. The information is for educational purpose of healthcare professionals and we are not liable for any loss or damage.

Core Prescribing Info

Contents

Romiplostim

Indications/Uses

Chronic ITP splenectomised adult patients who are refractory to other treatments (eg, corticosteroids, Ig). Adults w/ moderate to severe aplastic anaemia refractory to conventional therapies.

Dosage/Direction for Use

SC Chronic ITP Initially 1 mcg/kg once wkly. May be increased by increments of 1 mcg/kg until the patient achieves a platelet count ≥50 x 10⁹/L. Max: 10 mcg/kg once wkly. Aplastic anaemia Initially 10 mcg/kg once wkly. May be adjusted w/ increments of 5 mcg/kg. Consider dose increase in cases where platelet count has not risen (eg, increase by ≥20 × 10⁹/L from baseline or increase to ≥10 × 10⁹/L & ≥100% increase from baseline w/ blood transfusion independence) though the same dose has been administered for 4 consecutive wk. Max: 20 mcg/kg once wkly.

Contraindications

Hypersensitivity to romiplostim or E. coli-derived proteins.

MIMS Class

Haemostatics

ATC Classification

B02BX04 - romiplostim ; Belongs to the class of other systemic hemostatics. Used in the treatment of hemorrhage.

Regulatory Classification

POM

Presentation/Packing

Form

Romiplate powd for soln for inj 250 mcg/0.5 mL

Packing/Price

1's

Romiplate

romiplostim

Manufacturer:

Patheon Italia