Dissolution of cholesterol gallstones Adult 10 mg/kg daily as single dose to be taken at bedtime.
Patient weighing >100 kg Total daily dose: 1,250 mg (2 ½ tab),
81-100 kg Total daily dose: 1,000 mg (2 tab),
61-80 kg Total daily dose: 750 mg (1 ½ tab),
up to 60 kg Total daily dose: 500 mg (1 tab).
Symptomatic treatment of PBC 14 ± 2 mg/kg daily to be taken as divided doses over the day for the 1st 3 mth. May be taken once daily in the evening when liver function parameters improve.
Patient weighing >110 kg 1 tab (morning), 1 tab (midday), 1 ½ tab (evening) for the 1st 3 mth; subsequently, 3 ½ tab in the evening,
94-109 kg 1 tab (morning), 1 tab (midday), 1 tab (evening) for the 1st 3 mth; subsequently, 3 tab in the evening,
79-93 kg ½ tab (morning), 1 tab (midday), 1 tab (evening) for the 1st 3 mth; subsequently, 2 ½ tab in the evening,
63-78 kg ½ tab (morning), ½ tab (midday), 1 tab (evening) for the 1st 3 mth; subsequently, 2 tab in the evening,
47-62 kg ½ tab (morning), ½ tab (midday), ½ tab (evening) for the 1st 3 mth; subsequently, 1 ½ tab in the evening.