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Diovan (valsartan) is a nonpeptide, orally active, and specific angiotensin II receptor blocker acting on the AT1 receptor subtype.
Valsartan is chemically described as N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl) [1,1'-biphenyl]-4-yl]methyl]-L-valine. Its empirical formula is C24H29N5O3, and its molecular weight is 435.5.
Valsartan is a white to practically white fine powder. It is soluble in ethanol and methanol and slightly soluble in water.
Diovan is available as tablets for oral administration, containing 80 mg or 160 mg of valsartan.
80 mg tablets are pale red, almond-shaped, unscored, with beveled edges, imprinted NVR/DV.
160 mg tablets are grey-orange, almond-shaped, unscored, with beveled edges, imprinted NVR/DXDX.
Excipients/Inactive Ingredients: The inactive ingredients of the tablets are colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, iron oxides (yellow, black and/or red), magnesium stearate, microcrystalline cellulose, polyethylene glycol 8000, and titanium dioxide.
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