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Posology: One sustained release tablet per 24 hours, preferably in the morning, to be swallowed whole with water and not chewed.
At higher doses the antihypertensive action of indapamide is not enhanced but the saluretic effect is increased.
In case one or several doses have been missed: do not take a double dose the day after the omitted doses.
Special populations: Renal impairment (see "Contraindications" and "Precautions"): In severe renal failure (creatinine clearance below 30 mL/min), treatment is contraindicated.
Thiazide and related diuretics are fully effective only when renal function is normal or only minimally impaired.
Hepatic impairment: (see "Contraindications" and "Precautions"): In severe hepatic impairment, treatment is contraindicated.
Elderly (see "Precautions"): In the elderly, the plasma creatinine must be adjusted in relation to age, weight and gender. Elderly patients can be treated with Natrilix SR when renal function is normal or only minimally impaired.
Paediatric population: The safety and efficacy of Natrilix SR in children and adolescents have not been established. No data are available.
Method of administration: Oral use.
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