Pharmacology: Mechanism of Action: Pitavastatin competitively inhibits HMG-CoA reductase, an enzyme involved in the biosynthesis of cholesterol, thereby reducing cholesterol synthesis in the liver. As a result, there is an upregulation of LDL receptors, leading to increased uptake of LDL from the blood into the liver and a subsequent decrease in plasma total cholesterol (TC). Continued inhibition of hepatic cholesterol synthesis also reduces very low-density lipoprotein (VLDL) levels.