Sign Out
Utrogestan capsules may interfere with the effects of bromocriptine and may raise the plasma concentration of cyclosporine.
Utrogestan capsules may affect the results of laboratory tests of hepatic and/or endocrine functions.
Metabolism of Utrogestan capsules is accelerated by rifamycin an antibacterial agent.
The metabolism of progesterone by human liver microsomes was inhibited by ketoconazole (IC50 <0.1 μm). Ketoconazole is a known inhibitor of cytochrome P450 3A4. These data therefore suggest that ketoconazole may increase the bioavailability of progesterone. The clinical relevance of the in vitro findings is unknown.
Lanjutkan dengan Google