Xylocaine Injection Use In Pregnancy & Lactation

Use in pregnancy - Category A: The safe use of lidocaine during pregnancy has not been established. Although lidocaine has been used extensively for surgical procedures during pregnancy with no reports of ill effects to mother or foetus, there are no adequate or well-controlled studies in pregnant women of the effect of lidocaine on the developing foetus.
Lidocaine has been effectively used for obstetrical analgesia and adverse effects on the course of labour or delivery are rare. After epidural administration of lidocaine to women in labour, lidocaine crosses the placental barrier. However, concentrations in umbilical veins are lower than those found in the maternal circulation. It has been suggested that blood glucose levels should be checked in newborns after obstetric regional anaesthesia.
Note: Paracervical blocks may be associated with foetal bradycardia (see Precautions).
Use during lactation: Lidocaine passes into breast milk. The amount of lidocaine appearing in breast milk from a nursing mother receiving parenteral lidocaine is unlikely to lead to a significant accumulation of the parent drug in the breastfed infant. The remote possibility of an idiosyncratic or allergic reaction in the breastfed infant from lidocaine remains to be determined.