Discontinue use if the patient experience insomnia, palpitation, dizziness. Glaucoma, prostate hypertrophy, hyperthyroidism, urinary retention, heart disorders, DM. Concomitant use w/ other CNS depressants. Patients w/ or potential to develop HTN or stroke eg, overwt. May impair ability to drive or operate machinery. Liver & kidney dysfunction. Not recommended in pregnancy & nursing women. Not recommended in childn <2 yr. Elderly. Pseudoephedrine: Discontinue use if posterior reversible encephalopathy & reversible cerebral vasoconstriction syndrome occur.