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Hypersensitivity to the active substance "ibuprofen" or to any of the excipients of this medicinal product. (See Description).
History of hypersensitivity reactions (e.g. bronchospasm, asthma, rhinitis or urticaria) in response to acetylsalicylic acid (ASA) or other non-steroidal anti-inflammatory drugs (NSAIDs).
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy.
Active, or history of recurrent peptic ulcer/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
Other active bleeding like cerebrovascular bleedings or colitis ulcerosa.
Severe kidney and/or liver insufficiency.
Hemorrhagic diathesis.
Third trimester of pregnancy (see Use in Pregnancy & Lactation).
Severe heart failure (NYHA Class IV).
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