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Symptoms: In general, overdose symptoms include nausea, gastralgia, vomiting (blood) and diarrhoea (blood), dizziness, spasms, nystagmus and diplopia, headache and tinnitus. In case of severe intoxication also renal function disorders, hypotension, decrease of consciousness and coma (it is not clear whether the renal function disorder is caused by the intoxication or by the concurrent hypotension). In serious poisoning metabolic acidosis may occur.
Management of overdose: There is no specific antidote for ibuprofen.
The stomach should be emptied as soon as possible. If possible, the patient should vomit. If the patient is unconscious, gastric lavage and correction of severe electrolyte abnormalities should be considered.
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