Lamido Adverse Reactions

Epilepsy: The following adverse reactions were identified during epilepsy clinical trials and should be considered alongside those seen in the bipolar disorder clinical trials and post-marketing sections for an overall safety profile of Lamotrigine.
Skin and Subcutaneous Tissue Disorders: Very Common: Skin rash. Rare: Stevens-Johnson syndrome. Very rare: Toxic epidermal necrolysis.
Blood and Lymphatic System Disorders: Very Rare: Haematological abnormalities (including, neutropenia, leucopenia, anaemia, thrombocytopenia, pancytopenia, aplastic anaemia, agranulocytosis), lymphadenopathy.
Haematological abnormalities and lymphadenopathy may or may not be associated with drug reaction with eosinophilia and systemic symptoms (DRESS)/hypersensitivity syndrome (see Precautions and Immune System Disorders as follows).
Immune System Disorders: Very Rare: Drug reaction with eosinophilia and systemic symptoms (DRESS)/Hypersensitivity syndrome.
Psychiatric Disorders: Common: Aggression, irritability. Very Rare: Tics, hallucinations, confusion.
Nervous System Disorders: Very Common: Headache. Common: Somnolence, insomnia, dizziness, tremor. Uncommon: Ataxia. Rare: Nystagmus.
Eye Disorders: Uncommon: Diplopia, blurred vision.
Gastrointestinal Disorders: Common: Nausea, vomiting, diarrhea.
Hepatobiliary Disorders: Very Rare: Increased liver function tests, hepatic dysfunction, hepatic failure.
Hepatic dysfunction usually occurs in association with hypersensitivity reactions but isolated cases have been reported without overt signs of hypersensitivity.
Musculoskeletal and Connective Tissue Disorders: Very Rare: Lupus-like reactions.
General Disorders and Administration Site Conditions: Common: Tiredness.
Bipolar Disorder: The following adverse reactions were identified during bipolar disorder clinical trials and should be considered alongside those seen in the epilepsy clinical trials and post-marketing sections for an overall safety profile of Lamotrigine.
Skin and Subcutaneous Tissue Disorders: Very Common: Skin rash. Rare: Stevens-Johnson syndrome.
Nervous System Disorders: Very Common: Headache. Common: Agitation, somnolence, dizziness.
Musculoskeletal and Connective Tissue Disorders: Common: Arthralgia.
General Disorders and Administration Site Conditions: Common: Pain, back pain.